The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis.
Meiotic recombination is essential for the repair of programmed double strand breaks (DSBs) to generate crossovers (COs) during meiosis.The efficient processing of meiotic recombination intermediates not only needs various resolvases but also requires proper meiotic chromosome structure.The Smc5/6 complex belongs to the structural maintenance of ch